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T23521 |
VULM 1457
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Acyltransferase
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VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of... |
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T23550 |
YM-750
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YM 750 |
Acyltransferase
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YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest... |
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T8314 |
RP-64477
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RP64477 |
Acyltransferase
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RP-64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor. |
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T25651 |
Lecimibide
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DuP128,DuP-128,DuP 128 |
Acyltransferase
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Lecimibide (DuP 128) is a potent and selective inhibitor of acyl coenzyme A: cholesterol acyltransferase (ACAT), which can be used to study diseases due to high lipids. |
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T27245L |
Eflucimibe
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L0081,F-12511 |
Acyltransferase
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Eflucimibe (L0081) is an acyl coenzyme A: cholesterol acyltransferase inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, and can be used to study atherosclerosis and hyperlipidem... |
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T2753 |
Avasimibe
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PD-148515,CI-1011 |
P450
,
Acyltransferase
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Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenz... |
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T36126 |
TMP-153
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Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and choleste... |
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T70575 |
AS 183
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AS 183 is an inhibitor of cholesterol acyltransferase (ACAT). |
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T15187 |
E-5324
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Others
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T28820 |
SMP-797 HCl
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SMP-797,SMP 797,SMP797 |
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SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia. |
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T40553 |
ACAT-IN-6
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ACAT-IN-6, an acyl-Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor, displays potent inhibition of NF-κB mediated transcription. |
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T26548 |
Acaterin
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Acaterin, an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT), inhibits synthesis of cholesteryl ester in macrophage J774. |
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T39415 |
ACAT-IN-9
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ACAT-IN-9, acts as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). By doing so, it effectively suppresses NF-κB mediated transcription. |
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T70300 |
Avasimibe sodium
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Avasimibe sodium is an acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. |
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T39414 |
ACAT-IN-7
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ACAT-IN-7 is a compound that acts as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT) enzyme. It effectively suppresses the transcription process mediated by NF-κB. |
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T39417 |
ACAT-IN-2
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ACAT-IN-2 is a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). This compound effectively blocks NF-κB mediated transcription. |
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T40551 |
ACAT-IN-3
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ACAT-IN-3, a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), effectively suppresses NF-κB dependent transcription. |
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T39413 |
ACAT-IN-8
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ACAT-IN-8 (example 206) is a compound that functions as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), an enzyme involved in cholesterol modulation. This compound also possesses the ability to inhib... |
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T39416 |
ACAT-IN-4 hydrochloride
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ACAT-IN-4 hydrochloride (Example 208) is a hydrochloride salt of a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). This compound effectively hinders NF-κB mediated transcription. |
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T40552 |
ACAT-IN-10
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ACAT-IN-10 is an acyl-Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. It inhibits NF-κB mediated transcription with a weak activity. |
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T35603 |
Oleic Acid-2,6-diisopropylanilide
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AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol ac... |
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T40554 |
ACAT-IN-4
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ACAT-IN-4 (Example 208) is a chemical compound that functions as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). Additionally, ACAT-IN-4 effectively inhibits the transcription process mediated by NF-... |
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T39411 |
ACAT-IN-10 dihydrochloride
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ACAT-IN-10 dihydrochloride is a compound that serves as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT).ACAT-IN-10 dihydrochloride effectively hampers NF-κB mediated transcription, albeit to a lesser ... |
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T39412 |
ACAT-IN-5
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ACAT-IN-5 (example 19) is a compound that functions as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). By inhibiting ACAT, this compound effectively suppresses the transcription mediated by NF-κB. |
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T63036 |
CP-113818
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CP-113818 is a potent inhibitor of cholesterol acyltransferase (ACAT) and can be used to study Alzheimer's disease. |
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T36549 |
CAY10486
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Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of athe... |
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T35984 |
CAY10485
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Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of athe... |
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T70356 |
F-1394
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F-1394 is an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. F-1394 both prevents the formation of atherosclerosis and accelerates its regression without affecting the serum TC level, indicating that F-1394 acts ... |
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T37554 |
Oleyl Anilide
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AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransfera... |
